Environmental and Genetic Variables Influencing Mitochondrial Health and Parkinson’s Disease Penetrance
نویسندگان
چکیده
منابع مشابه
Genetic basis of Parkinson’s disease: inheritance, penetrance, and expression
Parkinson's disease can be caused by rare familial genetic mutations, but in most cases it is likely to result from an interaction between multiple genetic and environmental risk factors. Over recent years, many variants in a growing number of genes involved in the pathogenesis of Parkinson's disease have been identified. Mutations in several genes have been shown to cause familial parkinsonism...
متن کاملMitochondrial DNA and genetic disease.
From their very beginning to the present day, mitochondria have evolved to become a crucial organelle within the cell. The mitochondrial genome encodes only 37 genes, but its compact structure and minimal redundancy results in mutations on the mitochondrial genome being an important cause of genetic disease. In the present chapter we describe the up-to-date knowledge about mitochondrial DNA str...
متن کاملImpact of Environmental Quality Variables and Socio-Economic Factors on Human Health: Empirical Evidence from China
Carbon dioxide (CO2) is the foremost gas, emanated from human activities, and the best-known greenhouse gas, contributing to global warming, thus its negative effect on human health cannot be disregarded. The current paper investigates the relation between environmental quality variables, socio-economic factors, and human health from 1960 to 2014 in China, using Auto Regressive Distribution Lag...
متن کاملImpact of Environmental Quality Variables and Socio-Economic Factors on Human Health: Empirical Evidence from China
Carbon dioxide (CO2) is the foremost gas, emanated from human activities, and the best-known greenhouse gas, contributing to global warming, thus its negative effect on human health cannot be disregarded. The current paper investigates the relation between environmental quality variables, socio-economic factors, and human health from 1960 to 2014 in China, using Auto Regressive Distribution Lag...
متن کاملMicronuclei in neonates and children: effects of environmental, genetic, demographic and disease variables.
Children may be more susceptible to the effects of the environmental exposure and medical treatments than adults; however, limited information is available about the differences in genotoxic effects in children by age, sex and health status. Micronucleus (MN) assay is a well established method of monitoring genotoxicity, and this approach is thoroughly validated for adult lymphocytes by the Hum...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Parkinson's Disease
سال: 2018
ISSN: 2090-8083,2042-0080
DOI: 10.1155/2018/8684906